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POSTDOCTORAL POSITION IN CRYOBIOLOGY
The Hubbard lab (Department of Pharmacology, University of Alberta) is seeking a postdoctoral fellow to join their dynamic and enthusiastic research team. The successful candidate will work on a cryobiology project to assess the biochemical and biophysical properties of novel synthetic cryoprotective compounds, and examine their cryoprotective capacity in human cells, tissues, and possibly even organs (long-term objective). This project is part of a multidisciplinary collaboration being developed in conjunction with researchers in the Alberta Glycomics Centre. Techniques that will be employed include: nanolitre osmometry (to measure thermal hysteresis), ice recrystallization inhibitor (IRI) assays, primary and non-primary cell culture, various cell proliferation and viability assays (e.g. assessing RBC viability – Drabkin’s method), and optimizing freezing protocols using our programmable freezer. Longer-term objectives will involve dissection of murine tissues for cryopreservation, and subsequent assay of tissue damage and viability. In addition, the postdoc will have the opportunity to work on a second project investigating the mammalian genetics underlying cryopreservation. This position is for one year renewable for up to four years, depending on funding availability.
Date Posted on SfC website: 11/11/2016
Postdoctoral Position (posted October 2016)
A post-doctoral position is available immediately at the Biostabilization and Bioencapsulation Laboratories (http://biogels.umn.edu) at the Department of Mechanical Engineering at University of Minnesota. The position is focused on developing a novel method for room temperature stabilization and storage of human biospecimens, with specific emphasis on storage stabilization of proteinaceous cancer biomarkers.
Room temperature stabilization by isothermal vitrification requires less stringent processing and storage requirements for biospecimen processing, transport, and storage resulting in significant cost savings. Isothermal vitrification also helps avoid the physical, thermal, and chemical stresses imposed on macromolecules during processing and cryogenic storage, ensuring that the molecular information content of the biospecimens are preserved. Our group has developed an adsorbing/dissolving lyoprotectant matrix, and a complementary isothermal vitrification procedure to stabilize human serum (see a recent publication from our
We are looking for a highly motivated individual with a Ph.D. in Biochemistry, Chemistry, Chemical Engineering, Biomedical Engineering or Molecular Biology (or in a related field) with demonstrated competence, relevant expertise and having published high impact, innovative research publications. Experience in biospecimen science, and/or protein stabilization is desirable but not necessary.
The post-doctoral associate is expected to perform long term storage stability studies, and
Candidates must be enthusiastic and dedicated to science with excellent organizational skills and effective at working independently, while also collaborating and assisting the team reaching its collective research goal. Excellent verbal and written communication skills are required.
Application documents must be submitted online through the UMN employment system at: http://humanresources.umn.edu/jobs. Click on External Faculty and Staff Applicants, enter "313374" in the Job Opening ID, and change the Jobs Posted Within drop down menu to "anytime." At this point a username and password will need to be created to access thesystem.